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Mammals cannot be cloned indefinitely, mice study finds

Japanese researchers produced about 1,200 clones from one mouse over 20 years and found repeated cloning led to a "mutational meltdown".

Published Mar 24, 2026, 12:01 PM EDT | WFMZZ

Japanese scientists say there is a limit to how many times a mammal can be cloned before suffering a "mutational meltdown." Starting from a single mouse, they produced roughly 1,200 clones over two decades and observed accumulating genetic damage that culminated in the meltdown.